- 专利标题: METHOD OF PRODUCING COMPOUNDS HAVING HIV INTEGRASE INHIVITORY ACTIVITY
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申请号: EP18203589.9申请日: 2011-08-04
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公开(公告)号: EP3456721A2公开(公告)日: 2019-03-20
- 发明人: SUMINO, Yukihito , OKAMOTO, Kazuya , MASUI, Moriyasu , YAMADA, Daisuke , IKARASHI, Fumiya
- 申请人: Shionogi & Co., Ltd
- 申请人地址: 1-8, Doshomachi 3-chome Chuo-ku Osaka-shi, Osaka 541-0045 JP
- 专利权人: Shionogi & Co., Ltd
- 当前专利权人: Shionogi & Co., Ltd
- 当前专利权人地址: 1-8, Doshomachi 3-chome Chuo-ku Osaka-shi, Osaka 541-0045 JP
- 代理机构: Gladwin, Amanda Rachel
- 优先权: JP2010175899 20100805; JP2010277713 20101214
- 主分类号: C07D498/14
- IPC分类号: C07D498/14 ; C07D211/94 ; C07D213/80 ; A61K31/5365 ; A61P31/18 ; A61P43/00
摘要:
A process for preparing a compound represented by formula (Y1) or (Y2) [wherein R x is an optionally substituted carbocyclyl lower alkyl, or the like] or a salt thereof, using a novel process for preparing a pyridone derivative represented by formula (X4) [wherein R 1d is hydrogen, halogen, or the like; R 2d is hydrogen, a lower alkyl optionally substituted with substituent E, or the like; R 4d is a lower alkyl optionally substituted with substituent E, or the like; and R 6d is a lower alkyl group optionally substituted with substituent group E].
[Chemical formula 8]
[Chemical formula 8]
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