- 专利标题： PRIMARY CARBOXAMIDES AS BTK INHIBITORS
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申请号： EP18202730.0申请日： 2014-06-26
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公开(公告)号： EP3483167A1公开(公告)日： 2019-05-15
- 发明人: BONAFOUX, Dominique , DAVIS, Heather, M. , FRANK, Kristine, E. , FRIEDMAN, Michael, M. , HEROLD, J. Martin , HOEMANN, Michael, Z. , HUNTLEY, Raymond , OSUMA, Augustine , SHEPPARD, George , SOMAL, Gagandeep, K. , VAN CAMP, Jennifer , VAN EPPS, Stacy, A. , VASUDEVAN, Anil , WALLACE, Grier, A. , WANG, Lu , WANG, Lu , WANG, Zhi , WILSON, Noel, S. , XU, Xiangdong
- 申请人： AbbVie Inc.
- 申请人地址： 1 North Waukegan Road North Chicago, IL 60064 US
- 专利权人： AbbVie Inc.
- 当前专利权人： AbbVie Inc.
- 当前专利权人地址： 1 North Waukegan Road North Chicago, IL 60064 US
- 代理机构： Bond, Christopher William
- 优先权： US201361839729P 20130626; US201361897577P 20131030
- 主分类号： C07D513/04
- IPC分类号： C07D513/04 ; A61P35/00 ; A61K31/429
摘要：
The invention provides compounds of Formula (I)
pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
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