- 专利标题: BENZO-N-HYDROXY AMIDE COMPOUNDS HAVING ANTITUMOR ACTIVITY
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申请号: EP17737833.8申请日: 2017-07-14
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公开(公告)号: EP3484852A1公开(公告)日: 2019-05-22
- 发明人: STEVENAZZI, Andrea , SANDRONE, Giovanni , MODENA, Daniela , POZZI, Pietro, Samuele , VERGANI, Barbara , LATTANZIO, Maria , MASCAGNI, Paolo , STEINKÜHLER, Christian , FOSSATI, Gianluca
- 申请人: Italfarmaco SpA
- 申请人地址: Viale Fulvio Testi 330 20126 Milano IT
- 专利权人: Italfarmaco SpA
- 当前专利权人: Italfarmaco SpA
- 当前专利权人地址: Viale Fulvio Testi 330 20126 Milano IT
- 代理机构: Viganò, Elena
- 优先权: IT201600074606 20160718
- 国际公布: WO2018015292 20180125
- 主分类号: C07D215/14
- IPC分类号: C07D215/14 ; C07C259/10 ; C07D317/60 ; C07D405/12 ; C07D407/12 ; C07D209/18 ; C07D213/56 ; A61K31/16 ; A61K31/36 ; A61K31/438 ; A61K31/4406 ; A61P35/00 ; C07D213/643 ; C07D233/64
摘要:
The present invention relates to new benzo-N-hydroxy amide compounds of formula (I) and pharmaceutically acceptable salts thereof, which show a significant inhibitory activity on the proliferation of tumor cells and specifically of cancer stem cells.
公开/授权文献
- EP3484852B1 BENZO-N-HYDROXY AMIDE COMPOUNDS HAVING ANTITUMOR ACTIVITY 公开/授权日:2020-04-08
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