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公开(公告)号:EP3562810A1
公开(公告)日:2019-11-06
申请号:EP18716299.5
申请日:2018-04-12
申请人: Italfarmaco SpA
发明人: VERGANI, Barbara , CAPRINI, Gianluca , FOSSATI, Gianluca , LATTANZIO, Maria , MARCHINI, Mattia , PAVICH, Gianfranco , PEZZUTO, Marcello , RIPAMONTI, Chiara , SANDRONE, Giovanni , STEINKÜHLER, Christian , STEVENAZZI, Andrea
IPC分类号: C07D249/12
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公开(公告)号:EP4192830A1
公开(公告)日:2023-06-14
申请号:EP21743366.3
申请日:2021-07-30
申请人: Italfarmaco SpA
发明人: MARCHINI, Mattia , VERGANI, Barbara , SANDRONE, Giovanni , ROCCHIO, Ilaria , KACHKOVSKYI, Georgii , CAPRINI, Gianluca , FOSSATI, Gianluca , STEINKÜHLER, Christian , STEVENAZZI, Andrea
IPC分类号: C07D413/14 , C07D413/08 , C07D417/14 , C07D487/04 , C07D487/10 , C07D471/10 , A61K31/4245 , A61K31/4439 , A61K31/41 , A61K31/4192 , A61K31/381 , A61K31/4035 , A61K31/427 , A61K31/496 , A61K31/4725
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公开(公告)号:EP3484852B1
公开(公告)日:2020-04-08
申请号:EP17737833.8
申请日:2017-07-14
申请人: Italfarmaco SpA
发明人: STEVENAZZI, Andrea , SANDRONE, Giovanni , MODENA, Daniela , POZZI, Pietro, Samuele , VERGANI, Barbara , LATTANZIO, Maria , MASCAGNI, Paolo , STEINKÜHLER, Christian , FOSSATI, Gianluca
IPC分类号: C07D215/14 , C07C259/10 , C07D317/60 , C07D405/12 , C07D407/12 , C07D209/18 , C07D213/56 , A61K31/16 , A61K31/36 , A61K31/438 , A61K31/4406 , A61P35/00 , C07D213/643 , C07D233/64
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公开(公告)号:EP3484852A1
公开(公告)日:2019-05-22
申请号:EP17737833.8
申请日:2017-07-14
申请人: Italfarmaco SpA
发明人: STEVENAZZI, Andrea , SANDRONE, Giovanni , MODENA, Daniela , POZZI, Pietro, Samuele , VERGANI, Barbara , LATTANZIO, Maria , MASCAGNI, Paolo , STEINKÜHLER, Christian , FOSSATI, Gianluca
IPC分类号: C07D215/14 , C07C259/10 , C07D317/60 , C07D405/12 , C07D407/12 , C07D209/18 , C07D213/56 , A61K31/16 , A61K31/36 , A61K31/438 , A61K31/4406 , A61P35/00 , C07D213/643 , C07D233/64
摘要: The present invention relates to new benzo-N-hydroxy amide compounds of formula (I) and pharmaceutically acceptable salts thereof, which show a significant inhibitory activity on the proliferation of tumor cells and specifically of cancer stem cells.
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