- 专利标题： PREVENTIVE OR THERAPEUTIC AGENT FOR HTLV-1-ASSOCIATED MYELOPATHY USING LOW-DOSE ANTI-CCR4 ANTIBODY
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申请号： EP18761682.6申请日： 2018-03-02
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公开(公告)号： EP3590535A1公开(公告)日： 2020-01-08
- 发明人: YAMANO Yoshihisa
- 申请人： St. Marianna University School of Medicine , Kyowa Kirin Co., Ltd.
- 申请人地址： 2-16-1 Sugao Miyamae-ku Kawasaki-shi Kanagawa 216-8511 JP
- 专利权人： St. Marianna University School of Medicine,Kyowa Kirin Co., Ltd.
- 当前专利权人： St. Marianna University School of Medicine,Kyowa Kirin Co., Ltd.
- 当前专利权人地址： 2-16-1 Sugao Miyamae-ku Kawasaki-shi Kanagawa 216-8511 JP
- 代理机构： Hoffmann Eitle
- 优先权： JP2017039506 20170302
- 国际公布： WO2018159845 20180907
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61K31/52 ; A61K31/573 ; A61K31/706 ; A61K38/13 ; A61K45/00 ; A61P19/00 ; A61P31/12 ; A61P35/02 ; A61P37/06 ; A61P43/00
摘要：
An object of the present invention is to provide a novel therapeutic or preventive agent for human T cell leukemia virus type-1 associated myelopathy (HAM) containing an anti-human CC-chemokine receptor 4 (CCR4) antibody or an antibody fragment thereof as an active ingredient, and characterized by the administration and dosage of the antibody or the antibody fragment thereof. The present invention relates to a therapeutic or preventative agent for HAM characterized in that an anti-human CCR4 antibody or an antibody fragment thereof is contained as an active ingredient and the antibody or the antibody fragment thereof is administered at a low dose.
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