- 专利标题: A METHOD FOR PURIFYING ANTIBODIES
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申请号: EP19186573.2申请日: 2012-10-10
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公开(公告)号: EP3611187A1公开(公告)日: 2020-02-19
- 发明人: BERNETT, Matthew J. , MOORE, Gregory, L. , DESJARLAIS, John , RASHID, Rumana
- 申请人: Xencor, Inc.
- 申请人地址: 111 W. Lemon Avenue Monrovia, CA 91016 US
- 专利权人: Xencor, Inc.
- 当前专利权人: Xencor, Inc.
- 当前专利权人地址: 111 W. Lemon Avenue Monrovia, CA 91016 US
- 代理机构: HGF Limited
- 优先权: US201161545498P 20111010; US201261593846P 20120201; US201261598686P 20120214; US201213568028 20120806
- 主分类号: C07K16/00
- IPC分类号: C07K16/00 ; C07K16/46
摘要:
The invention relates generally to compositions and methods for purifying the desired species from a mixture of desired heterodimer and contaminating homodimer immunoglobulin variants by modifying the isoelectric point(s) of the individual chains.
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