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公开(公告)号:EP3928788A1
公开(公告)日:2021-12-29
申请号:EP21173790.3
申请日:2015-11-25
申请人: Xencor, Inc.
发明人: MOORE, Gregory , DESJARLAIS, John , BERNETT, Matthew , CHU, Seung , RASHID, Rumana , MUCHHAL, Umesh , LEE, Sung-Hyung
摘要: The present invention is directed to novel heterodimeric antibodies.
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公开(公告)号:EP3927728A2
公开(公告)日:2021-12-29
申请号:EP20714054.2
申请日:2020-02-21
申请人: Xencor, Inc.
发明人: MOORE, Gregory , VARMA, Rajat , KIM, Yoon, Kyung , RASHID, Rumana , CHANG, Eric , NISTHAL, Alex , DIAZ, Juan , BERNETT, Matthew , HEDVAT, Michael
IPC分类号: C07K14/54
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公开(公告)号:EP3526241A1
公开(公告)日:2019-08-21
申请号:EP17804322.0
申请日:2017-10-16
申请人: Xencor, Inc.
IPC分类号: C07K14/54 , C07K14/715 , C07K19/00
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公开(公告)号:EP2943511A1
公开(公告)日:2015-11-18
申请号:EP14738267.5
申请日:2014-01-14
申请人: Xencor, Inc.
IPC分类号: C07K16/46
CPC分类号: C07K16/468 , C07K16/2803 , C07K16/2809 , C07K16/2896 , C07K2317/31 , C07K2317/51 , C07K2317/515 , C07K2317/52 , C07K2317/528 , C07K2317/55 , C07K2317/565 , C07K2317/622 , C07K2317/64 , C07K2317/94
摘要: The invention provides novel heterodimeric proteins including heterodimeric antibodies.
摘要翻译: 本发明提供了包括异二聚体抗体的新型异二聚体蛋白。
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公开(公告)号:EP2766392A1
公开(公告)日:2014-08-20
申请号:EP12783743.3
申请日:2012-10-10
申请人: Xencor, Inc.
CPC分类号: C07K16/468 , C07K1/18 , C07K16/00 , C07K16/22 , C07K2317/24 , C07K2317/31 , C07K2317/52 , C07K2317/522 , C07K2317/524 , C07K2317/526 , C07K2317/53 , C07K2317/72 , C07K2317/94
摘要: The invention relates generally to compositions and methods for purifying the desired species from a mixture of desired heterodimer and contaminating homodimer immunoglobulin variants by modifying the isoelectric point(s) of the individual chains.
摘要翻译: 本发明一般涉及通过修饰各个链的等电点从期望的异二聚体和污染的同二聚体免疫球蛋白变体的混合物纯化所需物质的组合物和方法。
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公开(公告)号:EP4059514A1
公开(公告)日:2022-09-21
申请号:EP22155270.6
申请日:2016-04-28
申请人: Xencor, Inc.
发明人: MOORE, Gregory , DESLARLAIS, John , BERNETT, Matthew , CHU, Seung , RASHID, Rumana , MUCHHAL, Umesh , LEE, Sung-Hyung
摘要: The present invention is directed to novel heterodimeric antibodies.
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公开(公告)号:EP4050032A1
公开(公告)日:2022-08-31
申请号:EP22156183.0
申请日:2017-06-28
申请人: Xencor, Inc.
发明人: MOORE, Gregory , RASHID, Rumana , LEE, Sung-Hyung , FOSTER, Paul
摘要: The present invention is directed to antibodies, including novel antigen binding domains and heterodimeric antibodies, that bind somatostatin receptor 2 (SSTR2).
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公开(公告)号:EP4041303A1
公开(公告)日:2022-08-17
申请号:EP20811130.2
申请日:2020-10-09
申请人: Genentech, Inc. , Xencor, Inc.
发明人: DESJARLAIS, John , BERNETT, Matthew , HEDVAT, Michael , VARMA, Rajat , SCHUBBERT, Suzanne , BONZON, Christine , RASHID, Rumana , DIAZ, Juan , HOLDER, Patrick , HUANG, Christine
IPC分类号: A61K39/395 , A61P35/00 , C07K14/54 , C07K14/715 , C07K16/08 , C07K16/28 , A61K39/00
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