- 专利标题： PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS
-
申请号： EP19207235.3申请日： 2015-12-29
-
公开(公告)号： EP3623372A1公开(公告)日： 2020-03-18
- 发明人: IOANNIDIS, Stephanos , TALBOT, Adam Charles , FOLLOWS, Bruce , BUCKMELTER, Alexandre Joseph , WANG, Minghua , CAMPBELL, Ann-Marie , SCHMIDT, Darby Rye , GUERIN, David Joseph , CARAVELLA, Justin A , DIEBOLD, R. Bruce , ERICSSON, Anna , LANCIA, David R., Jr.
- 申请人： Forma Therapeutics, Inc.
- 申请人地址： 500 Arsenal St., Suite 100 Watertown, MA 02472 US
- 专利权人： Forma Therapeutics, Inc.
- 当前专利权人： Forma Therapeutics, Inc.
- 当前专利权人地址： 500 Arsenal St., Suite 100 Watertown, MA 02472 US
- 代理机构： Oates, Edward Christopher
- 优先权： US201462098141P 20141230
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K31/519 ; A61P3/10 ; A61P9/00 ; A61P25/28 ; A61P35/00
摘要：
The invention relates to inhibitors of USP7 inhibitors useful in the treatment of cancers, neurodegenerative diseases, immunological disorders, inflammatory disorders, cardiovascular diseases, ischemic diseases, viral infections and diseases, and bacterial infections and diseases, having the Formula:
where m, n, X 1 , X 2 , R 1 -R 5 , R 5' and R 6 are described herein.
where m, n, X 1 , X 2 , R 1 -R 5 , R 5' and R 6 are described herein.
信息查询
