- 专利标题： TREATMENT OF CANCER WITH A COMBINATION OF RADIATION, CERIUM OXIDE NANOPARTICLES, AND A CHEMOTHERAPEUTIC AGENT
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申请号： EP19207165.2申请日： 2015-07-17
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公开(公告)号： EP3628308A1公开(公告)日： 2020-04-01
- 发明人: BAKER, Cheryl
- 申请人： BioCurity Pharmaceuticals Inc.
- 申请人地址： 110 Front Street, Suite 300 Jupiter, FL 33477 US
- 专利权人： BioCurity Pharmaceuticals Inc.
- 当前专利权人： BioCurity Pharmaceuticals Inc.
- 当前专利权人地址： 110 Front Street, Suite 300 Jupiter, FL 33477 US
- 代理机构： Bond, Christopher William
- 优先权： US201462025861P 20140717
- 主分类号： A61K9/14
- IPC分类号： A61K9/14 ; A61K33/24 ; A61P35/00 ; A61K31/7068 ; A61K31/337 ; A61K9/00 ; A61K9/107 ; A61K45/06
摘要：
The present invention is directed to methods for the treatment of cancer with a combination of radiation, cerium oxide nanoparticles and at least one chemotherapeutic agent. Cerium oxide nanoparticles (CONPs) are nanometer-sized crystals of cerium oxide, typically ranging between about one nanometer to about 20 nanometers in longest dimension. The present methods use cerium oxide nanoparticles to enhance radiation-induced and chemotherapy-induced cancer cell death and also reduce the toxicity associated with radiation therapy and chemotherapy
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