- 专利标题： INHIBITING FATTY ACID SYNTHASE (FASN)
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申请号： EP19202580.7申请日： 2019-10-10
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公开(公告)号： EP3636637A1公开(公告)日： 2020-04-15
- 发明人: Martin, Matthew W. , Zablocki, Mary-Margaret , Mente, Scot , Dinsmore, Christopher , Wang, Zhongguo , Zheng, Xiaozhang
- 申请人： Forma Therapeutics, Inc.
- 申请人地址： 500 Arsenal St., Suite 100 Watertown, MA 02472 US
- 专利权人： Forma Therapeutics, Inc.
- 当前专利权人： Forma Therapeutics, Inc.
- 当前专利权人地址： 500 Arsenal St., Suite 100 Watertown, MA 02472 US
- 代理机构： Oates, Edward Christopher
- 优先权： US201862744071P 20181010; TW108136774 20191009
- 主分类号： C07D221/20
- IPC分类号： C07D221/20 ; C07D401/06 ; C07D401/10 ; C07D405/06 ; C07D405/14 ; C07D409/14 ; C07D413/06 ; C07D413/10 ; C07D413/14 ; A61P1/16 ; A61K31/438
摘要：
The present disclosure is directed to inhibitors of FASN. The compounds can be useful in the treatment of disease or disorders associated with the inhibition of FASN. For instance, the disclosure is concerned with compounds and compositions for inhibition of FASN, methods of treating, preventing, or ameliorating diseases or disorders associated with the inhibition of FASN, and methods of synthesis of these compounds.
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