发明公开
- 专利标题: ROTIGOTINE-CONTAINING PATCH
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申请号: EP18893071.3申请日: 2018-12-14
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公开(公告)号: EP3730129A1公开(公告)日: 2020-10-28
- 发明人: ARAKI Hiroyuki , TAKAGI Yuka , FUJIWARA Yoko , KOBAYASHI Hiroaki , KUROKAWA Takao
- 申请人: Hisamitsu Pharmaceutical Co., Inc.
- 申请人地址: 408, Tashirodaikan-machi Tosu-shi, Saga 841-0017 JP
- 专利权人: Hisamitsu Pharmaceutical Co., Inc.
- 当前专利权人: Hisamitsu Pharmaceutical Co., Inc.
- 当前专利权人地址: 408, Tashirodaikan-machi Tosu-shi, Saga 841-0017 JP
- 代理机构: Grünecker Patent- und Rechtsanwälte PartG mbB
- 优先权: JP2017242845 20171219; JP2018143868 20180731
- 国际公布: WO2019124261 20190627
- 主分类号: A61K9/70
- IPC分类号: A61K9/70 ; A61K31/381 ; A61K47/10 ; A61K47/32 ; A61P25/16 ; C07D333/20
摘要:
The present invention provides a rotigotine-containing patch comprising: a backing layer; and an adhesive agent layer, wherein the adhesive agent layer contains rotigotine and/or a pharmaceutically acceptable salt thereof,
the adhesive agent layer further contains a styrene-based thermoplastic elastomer, a petroleum-based resin and/or a terpene-based resin, an aliphatic alcohol, and a cross-linked polyvinylpyrrolidone, and
in the adhesive agent layer, a mass ratio of a content of the rotigotine and/or the pharmaceutically acceptable salt thereof in terms of rotigotine free form and a content of the cross-linked polyvinylpyrrolidone (content of the rotigotine and/or the pharmaceutically acceptable salt thereof in terms of rotigotine free form : content of the cross-linked polyvinylpyrrolidone) is 10 : 3 to 1 : 3.
the adhesive agent layer further contains a styrene-based thermoplastic elastomer, a petroleum-based resin and/or a terpene-based resin, an aliphatic alcohol, and a cross-linked polyvinylpyrrolidone, and
in the adhesive agent layer, a mass ratio of a content of the rotigotine and/or the pharmaceutically acceptable salt thereof in terms of rotigotine free form and a content of the cross-linked polyvinylpyrrolidone (content of the rotigotine and/or the pharmaceutically acceptable salt thereof in terms of rotigotine free form : content of the cross-linked polyvinylpyrrolidone) is 10 : 3 to 1 : 3.
公开/授权文献
- EP3730129B1 ROTIGOTINE-CONTAINING PATCH 公开/授权日:2024-08-07
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