- 专利标题： BISPECIFIC ANTI CLAUDIN XCD3 ANTIBODIES FOR TREATMENT OF CLAUDIN EXPRESSING CANCER DISEASES
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申请号： EP20189087.8申请日： 2013-11-12
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公开(公告)号： EP3766903A3公开(公告)日： 2021-02-17
- 发明人: SAHIN, Ugur , TÜRECI, Özlem , STADLER, Christiane , HOLLAND, Julia , BÄHR-MAHMUD, Hayat , BEISSERT, Tim , PLUM, Laura , LE GALL, Fabrice , JENDRETZKI, Arne , FIEDLER, Markus
- 申请人： BioNTech SE , Astellas Pharma Inc. , TRON - Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg- Universität Mainz gemeinnützige GmbH
- 申请人地址： DE 55131 Mainz An der Goldgrube 12; JP Chuo-ku Tokyo 103-8411 5-1, Nihonbashi-Honcho 2-Chome; DE 55131 Mainz Freiligrathstrasse 12
- 代理机构： Schnappauf, Georg
- 优先权： WOPCT/EP2013/002270 20130730
- 主分类号： C07K16/28
- IPC分类号： C07K16/28
摘要：
The present disclosure provides binding agents that contain a binding domain that is specific for CD3 allowing binding to T cells and a binding domain that is specific for a tumor-associated claudin molecule and methods of using these binding agents or nucleic acids encoding therefor for treating cancer.
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