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公开(公告)号：EP4444342A1
公开(公告)日：2024-10-16
申请号：EP22834951.0
申请日：2022-12-08
申请人： BioNTech SE
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公开(公告)号：EP4419695A1
公开(公告)日：2024-08-28
申请号：EP22805814.5
申请日：2022-10-17
申请人： BioNTech SE , TRON - Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg- Universität Mainz gemeinnützige GmbH
发明人： PERKOVIC, Mario , BEISSERT, Tim
CPC分类号： C12N15/86 , A61P31/14 , A61P35/00 , C12N2770/3612120130101 , C12N2770/3613420130101
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公开(公告)号：EP4413040A1
公开(公告)日：2024-08-14
申请号：EP22802904.7
申请日：2022-10-05
申请人： Genmab A/S , BioNTech SE
发明人： MUIK, Alexander , NÜRMBERGER, Kristina , PENCHEVA, Nora , JURE-KUNKEL, Maria,N, , SAHIN, Ugur , FELLERMEIER-KOPF, Sina , GARRIDO CASTRO, Patricia , BLUM, Jordan , GIESEKE, Friedericke , BREIJ, Esther C. W. , GUELEN, Lars , NEIJSSEN, Joost , BECKMANN, Karsten , PAULMANN, Claudia , DE KREUK, Bart-Jan , HIBBERT, Richard , SCHUURMAN, Janine , LABRIJN, Aran , KUZMANOV, Ivan
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公开(公告)号：EP4401788A1
公开(公告)日：2024-07-24
申请号：EP22809018.9
申请日：2022-10-21
发明人： MORENO HERRERO, Jorge , HAAS, Heinrich , ERBAR, Stephanie , STAHL, Theo Benjamin , GARCIA FERNANDEZ, Jose Manuel , BENITO HERNANDEZ, Juan Manuel , LOPEZ FERNANDEZ, Jose , ORTIZ MELLET, Maria del Carmen , DE LA CRUZ RUIZ, Noelia , GONZALEZ CUESTA, Manuel , AMBULUDI, Egon Jack Jacobus , VLATKOVIC, Irena
CPC分类号： A61K47/549 , A61P31/12 , A61K9/0019 , A61K9/5123 , A61K47/543 , C12N15/88
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公开(公告)号：EP4398882A1
公开(公告)日：2024-07-17
申请号：EP22785696.0
申请日：2022-09-09
申请人： BioNTech SE
IPC分类号： A61K9/127
CPC分类号： A61K9/1272 , A61K9/0019
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公开(公告)号：EP4370551A1
公开(公告)日：2024-05-22
申请号：EP22750715.9
申请日：2022-07-13
申请人： BioNTech SE
发明人： SAHIN, Ugur , STADLER, Christiane , LINDEMANN, Claudia , ELLINGHAUS, Ursula , BÄHR-MAHMUD, Hayat , FISCHER, Leyla , CHATURVEDI, Anuhar , BOROS, Gábor , REINHOLZ, Jonas , BESSONOV, Sergey , KARIKÓ, Katalin
CPC分类号： C07K16/2809 , C07K16/28 , C07K2317/3120130101 , A61P35/00 , C07K2317/62220130101
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公开(公告)号：EP4359435A1
公开(公告)日：2024-05-01
申请号：EP22735846.2
申请日：2022-06-20
申请人： Genmab A/S , BioNTech SE
发明人： SAHIN, Ugur , MUIK, Alexander , FORSSMANN, Ulf , JURE-KUNKEL, Maria N. , BAJAJ, Gaurav , TALHAUSER, Craig , PENCHEVA, Nora
CPC分类号： C07K16/24 , C07K16/2827 , A61K2039/54520130101 , C07K2317/73420130101
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公开(公告)号：EP4326317A1
公开(公告)日：2024-02-28
申请号：EP22720733.9
申请日：2022-04-20
申请人： BioNTech SE
发明人： SAHIN, Ugur , MUIK, Alexander
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公开(公告)号：EP4285933A1
公开(公告)日：2023-12-06
申请号：EP22382517.5
申请日：2022-05-30
发明人： Moreno Herrero, Jorge , Haas, Heinrich , Erbar, Stephanie , Stahl, Theo Benjamin , Garcia Fernandez, Jose Manuel , Benito Hernandez, Juan Manuel , Lopez Fernandez, Jose , Ortiz Mellet, Maria del Carmen , de la Cruz Ruiz, Noelia , Gonzalez Cuesta, Manuel , Jacobus Ambuludi, Egon Jack , Vlatkovic, Irena
摘要： The present disclosure provides complexes i) a cationic oligosaccharide comprising one or more cationic moieties bonded to a trehalose, a sucrose, or a gluco-n-oligosaccharide moiety, where n is 2-6; ii) a surfactant; and iii) one or more additives selected from: a sterol, a helper lipid, an immunomodulator, and a targeting molecule; and used thereof
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公开(公告)号：EP4285932A1
公开(公告)日：2023-12-06
申请号：EP22382515.9
申请日：2022-05-30
发明人： Moreno Herrero, Jorge , Haas, Heinrich , Erbar, Stephanie , Garcia Fernandez, Jose Manuel , Benito Hernandez, Juan Manuel , Lopez Fernandez, Jose
摘要： The present disclosure provides complexes comprising a cationic oligosaccharide and an RNA, wherein the cationic oligosaccharide comprises a plurality of cationic moieties bonded to a trehalose, a sucrose, or a gluco-n-oligosaccharide moiety, where n is 2-6, and a ratio of N/P in the complex is less than 20:1
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