- 专利标题: SYRINGE WITH TWO-STAGE SEALING PRESSURE
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申请号: EP20197287.4申请日: 2013-03-14
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公开(公告)号: EP3777927A1公开(公告)日: 2021-02-17
- 发明人: MACKEY, Sean, E. , ZHOU, Ji , GIBLER, Martin, J. , LEE, Dennis , WIESNER, Bryan, L.
- 申请人: AbbVie Inc.
- 申请人地址: US North Chicago, IL 60064 1 North Waukegan Road
- 代理机构: Plasseraud IP
- 优先权: US201361763777 P 20130212
- 主分类号: A61M5/178
- IPC分类号: A61M5/178 ; A61M5/31 ; A61M5/315 ; A61J1/14 ; A61M5/00 ; A61J15/00 ; A61M5/145 ; A61J7/00
摘要:
A syringe includes a barrel, a plunger, and a sealing member creating a seal between the plunger and the barrel. The barrel includes a first portion with a first inner diameter and a second portion with a second inner diameter that is larger than the first inner diameter. The sealing member engages the first portion of the barrel to give rise to a first contact pressure when the barrel is filled with product. The first contact pressure is sufficient to maintain a gas-tight seal over the expected temperature ranges -25°C to 40°C. A first force is applied to the plunger to overcome the first contact pressure and move the plunger out of the first portion and into the second portion to dispense product. The sealing member engages the second portion of the barrel to give rise to a second contact pressure that is lower than the first contact pressure. A second force lower than the first force is sufficient to overcome the second contact pressure and move the plunger in the second portion to continue dispensing product. The syringe may include a restraining element for accommodating expansion of the product during freezing.
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