- 专利标题： METHODS FOR DETECTING CPG METHYLATION OF TUMOR-DERIVED DNA IN BLOOD SAMPLES
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申请号： EP20214665.0申请日： 2017-01-27
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公开(公告)号： EP3828281A1公开(公告)日： 2021-06-02
- 发明人: Lewin, Jörn , Kottwitz, Denise , Esche, Selina
- 申请人： Epigenomics AG
- 申请人地址： DE 10829 Berlin Geneststrasse 5
- 代理机构： Zwicker, Jörk
- 优先权： EP16153452 20160129
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68
摘要：
The present invention relates to the field of pharmacogenomics and in particular to detecting the presence or absence of methylated ANKRD13B and/or FOXF2 DNA derived from a tumor in blood or blood-derived samples or in other body fluids that contain DNA released from a tumor. This detection is useful for a minimally invasive diagnosis of cancers and the invention provides methods and oligonucleotides suitable for this purpose.
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