发明公开
- 专利标题： METHOTREXATE DOSAGE FORM
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申请号： EP20153818.8申请日： 2020-01-27
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公开(公告)号： EP3854385A1公开(公告)日： 2021-07-28
- 发明人: Højgaard, Bent , Damgaard Jensen, Hanne
- 申请人： ROS Therapeutics ApS
- 申请人地址： DK 2200 Copenhagen Ole Maaløes Vej 3
- 代理机构： Poulsen, Niels Jakob
- 主分类号： A61K9/20
- IPC分类号： A61K9/20 ; A61K9/48 ; A61K31/519 ; A61P17/06 ; A61P19/02 ; A61P35/02 ; A61K9/28
摘要：
The present invention relates to a pharmaceutical dosage form comprising an active ingredient such as methotrexate or a pharmaceutically acceptable salt thereof, in particular in the form of pellets, such as multiparticulates, mini-tablets or granulate. It further relates to oral dosage forms for which saturation kinetics limits the oral use of higher dosages of active ingredients.
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