公开(公告)号：EP3875572A1

公开(公告)日：2021-09-08

申请号：EP20212071.3

申请日：2020-12-06

申请人： Diversified Biotech, Inc.

发明人： PERLMAN, Daniel

IPC分类号： C12M1/22 ,  C12M1/00

摘要： 2D and 3D cell culture containers formed from blends of poly-L-lactide and poly-D-lactide provide growth surfaces for adherent cells and do not require surface treatment or coating to support mammalian cell growth. The cell culture containers are transparent, heat tolerant, and are environmentally degradable and suitable for composting in landfills.

公开(公告)号：EP3854385A1

公开(公告)日：2021-07-28

申请号：EP20153818.8

申请日：2020-01-27

申请人： ROS Therapeutics ApS

发明人： Højgaard, Bent ,  Damgaard Jensen, Hanne

IPC分类号： A61K9/20 ,  A61K9/48 ,  A61K31/519 ,  A61P17/06 ,  A61P19/02 ,  A61P35/02 ,  A61K9/28

摘要： The present invention relates to a pharmaceutical dosage form comprising an active ingredient such as methotrexate or a pharmaceutically acceptable salt thereof, in particular in the form of pellets, such as multiparticulates, mini-tablets or granulate. It further relates to oral dosage forms for which saturation kinetics limits the oral use of higher dosages of active ingredients.

公开(公告)号：EP2983706B1

公开(公告)日：2021-05-19

申请号：EP14722538.7

申请日：2014-04-10

发明人： BAHRAMI, Shervin ,  RYTTERGÅRD DUCH, Mogens ,  KANSTRUP HOLM, Christian ,  LASKA, Magdalena Janina

IPC分类号： A61K39/12 ,  C12N15/09

公开(公告)号：EP3680213A1

公开(公告)日：2020-07-15

申请号：EP19172078.8

申请日：2013-07-01

申请人： Northeastern University

发明人： BUSNAINA, Ahmed ,  YILMAZ, Cihan ,  KIM, TaeHoon ,  SOMU, Sivasumbramanian

IPC分类号： B81C1/00 ,  C25D5/02 ,  C25D13/02 ,  H01L21/768 ,  H01L21/288 ,  H01L21/76

摘要： A variety of homogeneous or layered hybrid nanostructures are fabricated by electric field-directed assembly of nanoelements. The nanoelements and the fabricated nanostructures can be conducting, semi-conducting, or insulating, or any combination thereof. Factors for enhancing the assembly process are identified, including optimization of the electric field and combined dielectrophoretic and electrophoretic forces to drive assembly. The fabrication methods are rapid and scalable. The resulting nanostructures have electrical and optical properties that render them highly useful in nanoscale electronics, optics, and biosensors.

公开(公告)号：EP2763696B1

公开(公告)日：2018-09-19

申请号：EP12781027.3

申请日：2012-10-05

申请人： iSD Immunotech ApS

发明人： RYTTERGÅRD DUCH, Mogens ,  BAHRAMI, Shervin

IPC分类号： A61K39/12 ,  C07K4/02 ,  C07K14/08

CPC分类号： C07K14/005 ,  A61K39/12 ,  C07K1/00 ,  C07K4/02 ,  C07K7/08 ,  C07K14/08 ,  C12N7/00 ,  C12N2760/12121 ,  C12N2760/12122 ,  C12N2760/12221 ,  C12N2760/12222 ,  C12N2760/16121 ,  C12N2760/16122 ,  C12N2760/16134 ,  C12N2760/16221 ,  C12N2760/16222 ,  C12N2760/16234 ,  C12N2760/16321 ,  C12N2760/16322 ,  C12N2770/24121 ,  C12N2770/24122 ,  C12N2770/24134 ,  C12N2770/24221 ,  C12N2770/24222 ,  C12N2770/24234 ,  C12N2770/24321 ,  C12N2770/24322 ,  C12N2770/28021 ,  C12N2770/28034 ,  C12N2770/36121 ,  C12N2770/36122 ,  C12N2770/36221 ,  C12N2770/36222

摘要： The present invention relates to enveloped RNA viruses. The invention in particular relates to the generation of superior antigens for mounting an immune response by first identifying then mutating the immunosuppressive domains in fusion proteins of enveloped RNA viruses resulting in decreased immunosuppressive properties of viral envelope proteins from the viruses.

公开(公告)号：EP3166432A1

公开(公告)日：2017-05-17

申请号：EP15818233.7

申请日：2015-07-10

申请人： Cohesive Systems LLC

发明人： GALLAGHER, Joseph, E.

IPC分类号： A41D27/24 ,  A41D31/02 ,  B32B37/12

CPC分类号： A41D27/02 ,  A41B11/005 ,  A41B11/01 ,  A41D1/06 ,  A41D19/001 ,  A41D19/01 ,  A41D27/245 ,  A41D31/02 ,  A41D2400/22 ,  A41H43/04 ,  A43B23/07 ,  B29C65/02 ,  B29C65/08 ,  B29C65/48 ,  B29C65/62 ,  B29C66/20 ,  B29C66/45 ,  B29C66/729 ,  B29C66/7294 ,  B29C66/7485 ,  B29L2031/48 ,  B29L2031/50 ,  B32B5/022 ,  B32B5/024 ,  B32B5/026 ,  B32B5/08 ,  B32B5/18 ,  B32B5/22 ,  B32B5/245 ,  B32B5/26 ,  B32B7/005 ,  B32B7/02 ,  B32B7/08 ,  B32B7/12 ,  B32B7/14 ,  B32B27/065 ,  B32B27/12 ,  B32B27/18 ,  B32B27/32 ,  B32B27/322 ,  B32B27/36 ,  B32B27/40 ,  B32B37/06 ,  B32B37/10 ,  B32B37/1018 ,  B32B37/12 ,  B32B37/144 ,  B32B37/182 ,  B32B38/1808 ,  B32B2038/008 ,  B32B2262/02 ,  B32B2262/0238 ,  B32B2262/0246 ,  B32B2262/0253 ,  B32B2262/0261 ,  B32B2262/0276 ,  B32B2262/0292 ,  B32B2262/06 ,  B32B2262/062 ,  B32B2262/08 ,  B32B2262/14 ,  B32B2264/108 ,  B32B2266/025 ,  B32B2305/022 ,  B32B2305/182 ,  B32B2305/188 ,  B32B2305/28 ,  B32B2307/724 ,  B32B2307/7265 ,  B32B2317/10 ,  B32B2323/10 ,  B32B2327/06 ,  B32B2327/18 ,  B32B2333/00 ,  B32B2367/00 ,  B32B2369/00 ,  B32B2375/00 ,  B32B2377/00 ,  B32B2437/00 ,  B32B2437/02

摘要： A process for fabricating a three-dimensional, multi-layered fabric product with a moisture barrier is provided. A partially seamed inner lining fabric assembly having at least a two-dimensional shape is laminated with a membrane barrier film having flaps left un-laminated to cover at least one seam. The inner lining fabric assembly is further seamed and flaps of the of the membrane barrier film overlapped into contact with each other and sealed to provide a continuous moisture barrier. A process for fabricating a stretchable section of a garment with a moisture barrier is also provided. At least a section of a garment is formed from fibers arranged in a pattern having a direction of stretch in one direction and a three-dimensional surface texture such that a portion of the fibers protrude above another portion of the fibers. The stretchable section is stretched in the direction of stretch. Segments of a membrane barrier film are adhered to an outer edge of the protruding portion of the fibers while the section is stretched in the direction of stretch, leaving intermediate segments of the barrier film free from adherence to the section. In this way, the intermediate segments of the membrane barrier film include slack that folds up to form ruches when the section is in a relaxed state.

摘要翻译： 提供了一种制造具有防潮层的三维多层织物产品的方法。 将具有至少二维形状的部分接缝的内衬织物组件与具有未层压的翼片以覆盖至少一个接缝的膜阻挡膜层压。 内衬织物组件进一步缝合，并且膜阻挡膜的折翼重叠成彼此接触并密封以提供连续的防潮层。 还提供了制造具有防潮层的服装的可拉伸部分的方法。 至少一部分衣服由纤维形成，所述纤维以在一个方向上具有拉伸方向和三维表面结构的图案布置，使得一部分纤维突出到另一部分纤维上方。 可拉伸部分沿拉伸方向拉伸。 膜阻挡膜的片段粘附到纤维的突出部分的外边缘，同时该部分在拉伸方向上拉伸，使得阻挡膜的中间部分不粘附到该部分。 以这种方式，膜阻挡膜的中间段包括当该部分处于松弛状态时折叠起来以形成裂纹的松弛。

公开(公告)号：EP3063308A1

公开(公告)日：2016-09-07

申请号：EP14857570.7

申请日：2014-11-03

申请人： Kinalco, Inc.

发明人： UELAND, Stian, M. ,  DAVE, Vivek, R.

IPC分类号： C22F1/00 ,  A61L31/14 ,  F03G7/06

CPC分类号： C22C38/58 ,  A61L31/022 ,  A61L31/14 ,  A61L2400/16 ,  C21D2201/01 ,  C21D2211/001 ,  C21D2211/008 ,  C22C5/02 ,  C22C9/01 ,  C22C9/02 ,  C22C9/04 ,  C22C20/00 ,  C22C22/00 ,  C22C28/00 ,  C22C30/02 ,  C22C30/04 ,  C22C30/06 ,  C22C38/002 ,  C22C38/02 ,  C22C38/04 ,  C22C38/105 ,  C22C38/12 ,  C22C38/14 ,  C22C38/34 ,  C22F1/006 ,  F03G7/065 ,  H01B1/02 ,  H01B7/0009 ,  H01B7/40 ,  H04R1/1033 ,  H04R5/033

摘要： A conductor that resists plastic deformation is provided for an electronic signal-carrying or electric power-carrying cable, cable assembly, or device. The conducting element itself has favorable mechanical properties and therefore combines plastic deformation resistance with conductance. In one embodiment, the superelastic conductor is fabricated using a shape memory alloy such that the transformation temperature of the superelastic conductor is set outside the useful operating range of the conductor. In another embodiment, the conductor is fabricated using a shape memory alloy that is nominally in a martensitic phase under stress free conditions. In both embodiments, the conductor microstructures are able to accommodate externally applied strain, bending, deformation, or other external displacement through mechanisms which do not involve plastic deformation.

公开(公告)号：EP3041460A1

公开(公告)日：2016-07-13

申请号：EP14776569.7

申请日：2014-09-01

申请人： Unigroup ApS

发明人： LICHT, Flemming

IPC分类号： A61K8/37 ,  A61Q19/00 ,  A61K8/97 ,  A61P17/10

CPC分类号： A61K8/37 ,  A61K8/97 ,  A61K2800/524 ,  A61Q19/00 ,  A61Q19/005

摘要： The present invention relates to a composition comprising ethyl lactateand kigelia. In particular, it relates to a dermatological composition for the treatment of acneand/or diaper dermatitis.

摘要翻译： 本发明涉及包含乳酸乙酯和小菜蛾的组合物。 特别涉及用于治疗痤疮/或尿布性皮炎的皮肤病学组合物。

公开(公告)号：EP2859007A1

公开(公告)日：2015-04-15

申请号：EP14757837.1

申请日：2014-07-14

申请人： Asiros A/S

发明人： SLOTH WEIDNER, Morten ,  SLOTH WEIDNER, Ida

IPC分类号： C07H19/044 ,  C07H7/04 ,  A61K36/18 ,  A23L1/03

CPC分类号： A61K31/7032 ,  A23L33/105 ,  A23V2002/00 ,  A61K31/185 ,  A61K36/185 ,  A61K45/06 ,  C07H7/04 ,  C07H15/10 ,  C07H15/18 ,  C07H19/04 ,  C07H19/044 ,  C12P19/28 ,  C12P19/44

摘要： The present invention relates to a novel alkaloid and novel bioactive alkaloid fractions derivable from Ribes preferably selected among Ribes Rubrum and Ribes nigrum; methods of manufacturing such bioactive Ribes alkaloid fractions and their use for the inhibition of IKK-&bgr;, PDE4 and/or PDE5 and in addition their promoting effect on mitochondrial biogenesis and function; their therapeutic or non-therapeutic applications as nutritive or medicinal products in the management of conditions associated with impaired mitochondrial function or IKK-&bgr;, PDE4 and/or PDE5 activity, such as inflammation, neurodegeneration, dyslipidemia, type 2 diabetes mellitus, impaired wound healing, sarcopenia and other conditions associated with muscle dysfunction or tiredness and fatigue, or where optimization of muscular or cognitive function is desired; extracts, juices or concentrates of Ribes comprising such alkaloids; compostions comprising such alkaloids, including pharmaceutical compositions, nutritive product such as functional foods and nutraceutical compositions, and cosmetic compositions and medical devices.

公开(公告)号：EP2032031B1

公开(公告)日：2011-08-17

申请号：EP07719118.7

申请日：2007-06-27

申请人： SBC Research Pty Ltd

发明人： CORINO, Gary, L.

IPC分类号： A61B5/07 ,  G01N23/20 ,  G01N33/50

CPC分类号： G01N23/20 ,  G01N2333/4742