A structure for supporting sewing machines of articles, comprising: at least two components, a first component (2) and a second component (3), parallel to one another, defining the base of the structure; at least two opposite uprights (4, 5), each constrained inferiorly to a corresponding one of the components, upper heads (4A, 5A) of which are horizontal, and coplanar to one another, so as to define a plane (Z) for restingly receiving a sewing machine (M); at least a first cross-member (6) connecting the uprights; at least a second cross-member (7) connecting the components: a first and a second pair of wheels (12A-12B, 22A-22B), with the relative axes thereof being parallel to one another, borne by relative first and second means (10, 20) correspondingly supported by said first component (2) and second component; activating means for synchronously moving the pairs of wheels from a non-operating position (K), wherein the pairs of wheels are raised with respect to the support plane (P) abutted by said components (2, 3), to an operating position (H) wherein they intercept said support plane (P) with consequent raising with respect to the support plane (P) of the structure.