- 专利标题： PREDICTING IMMUNOGENICITY OF T CELL EPITOPES
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申请号： EP21159558.2申请日： 2014-05-07
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公开(公告)号： EP3895727A1公开(公告)日： 2021-10-20
- 发明人: SAHIN, Ugur , TADMOR, Arbel David , CASTLE, John Christopher , BOEGEL, Sebastian , LÖWER, Martin
- 申请人： BioNTech RNA Pharmaceuticals GmbH , TRON - Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg- Universität Mainz gemeinnützige GmbH
- 申请人地址： DE 55131 Mainz An der Goldgrube 12; DE 55131 Mainz Freiligrathstrasse 12
- 代理机构： Schnappauf, Georg
- 优先权： WOPCT/EP2013/001400 20130510
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; G16B20/00
摘要：
The present invention relates to methods for predicting T cell epitopes. In particular, the present invention relates to methods for predicting whether modifications in peptides or polypeptides such as tumor-associated neoantigens are immunogenic or not. The methods of the invention are useful, in particular, for the provision of vaccines which are specific for a patient's tumor and, thus, in the context of personalized cancer vaccines.
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