- 专利标题： FLUORINE-CONTAINING SUBSTITUTED BENZOTHIOPHENE COMPOUND, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF
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申请号： EP19907455.0申请日： 2019-12-31
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公开(公告)号： EP3907221A1公开(公告)日： 2021-11-10
- 发明人: ZHANG, Ao , GENG, Meiyu , DING, Chunyong , XIE, Zuoquan , DING, Jian , ZHANG, Yan , SHEN, Ancheng , WANG, Xiyuan
- 申请人： Shanghai Institute of Materia Medica, Chinese Academy of Sciences
- 申请人地址： CN Pudong, Shanghai 201203 555 Zu Chong Zhi Road Zhang Jiang
- 代理机构： Predazzi, Valentina
- 优先权： CN201910002749 20190102
- 国际公布： WO2020140894 20200709
- 主分类号： C07D333/60
- IPC分类号： C07D333/60 ; C07D333/58 ; C07D333/56 ; C07D409/12 ; A61K31/381 ; A61P35/00
摘要：
The present invention relates to fluorine-containing substituted benzothiophene compound, and a pharmaceutical composition and an application thereof. Specifically, the compound of the present invention has the structure as shown in formula I, wherein the definitions of each group and substituent are as described in the description. The present invention further discloses a preparation method of the compound and an anti-tumor application thereof.
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