- 专利标题: BINDING MOLECULES FOR BCMA AND CD3
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申请号: EP21158075.8申请日: 2014-03-14
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公开(公告)号: EP3912997A3公开(公告)日: 2021-12-15
- 发明人: KUFER, Peter , RAUM, Tobias , HOFFMANN, Patrick , KISCHEL, Roman , LUTTERBUESE, Ralf , RAU, Doris , ADAM, Paul , BORGES, Eric , HEBEIS, Barbara , HIPP, Susanne
- 申请人: Amgen Research (Munich) GmbH , Amgen Inc.
- 申请人地址: DE 81477 München Staffelseestrasse 2; US Thousand Oaks, CA 91320-1799 One Amgen Center Drive
- 代理机构: Dörries, Hans Ulrich
- 优先权: US201361793235 P 20130315
- 主分类号: C07K16/28
- IPC分类号: C07K16/28
摘要:
The present invention relates to a binding molecule comprising a first and a second binding domain, wherein the first binding domain is capable of binding to epitope clusters of BCMA, and the second binding domain is capable of binding to the T cell CD3 receptor complex. Moreover, the invention provides a nucleic acid sequence encoding the binding molecule, a vector comprising said nucleic acid sequence and a host cell transformed or transfected with said vector. Furthermore, the invention provides a process for the production of the binding molecule of the invention, a medical use of said binding molecule and a kit comprising said binding molecule.
公开/授权文献
- EP3912997A2 BINDING MOLECULES FOR BCMA AND CD3 公开/授权日:2021-11-24
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