- 专利标题： SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS
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申请号： EP21183553.3申请日： 2019-04-05
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公开(公告)号： EP3939658A1公开(公告)日： 2022-01-19
- 发明人: KOTIAN, Pravin L. , BABU, Yarlagadda S. , ZHANG, Weihe , LU, Peng-Cheng , WU, Minwan , LV, Wei , NGUYEN, Trung Xuan , DANG, Zhao , CHINTAREDDY, Venkat R. , KUMAR, V. Satish , RAMAN, Krishnan
- 申请人： Biocryst Pharmaceuticals, Inc.
- 申请人地址： US Durham, North Carolina 27703 4505 Emperor Blvd. Suite 200
- 代理机构： EIP
- 优先权： US201862654108 P 20180406
- 主分类号： A61P9/00
- IPC分类号： A61P9/00 ; A61P13/12 ; A61P25/28 ; A61P37/00 ; C07D209/08 ; C07D231/56 ; C07D235/08 ; C07D239/70 ; C07D261/20 ; C07D307/79 ; C07D333/54 ; C07D403/10 ; C07D405/12 ; C07D407/04 ; C07D407/10 ; C07D409/12 ; C07D471/04 ; C07D487/04 ; C07D307/81
摘要：
Disclosed are compounds of formulae I and II, and pharmaceutically acceptable salts and prodrugs thereof, which are inhibitors of the complement system. Also provided are pharmaceutical compositions comprising such a compound, and methods of using the compounds and compositions in the treatment or prevention of a disease or condition characterized by aberrant complement system activity.
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