发明公开
- 专利标题： PREPARATION METHOD FOR AMIDE COMPOUND AND APPLICATION THEREOF IN FIELD OF MEDICINE
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申请号： EP20778681.5申请日： 2020-03-24
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公开(公告)号： EP3950676A1公开(公告)日： 2022-02-09
- 发明人: XU, Xin , CHEN, Jia , ZHANG, Zhen , ZHANG, Liming , WU, Qimei , JIANG, Qingyun , GUO, Fengying , ZHANG, Yuyun , YU, Hao , WANG, Ying , SUN, Kang , ZANG, Chengxu , QIN, Chenggang , ZHOU, Xiaobo , ZHANG, Xiaojuan , WANG, Yijin , XIA, Xiaoer , LI, Yunfei , GE, Jian
- 申请人： Shanghai Synergy Pharmaceutical Sciences Co., Ltd , Zhejiang Huahai Pharmaceutical Co., Ltd.
- 申请人地址： CN Shanghai 201203 Zhangheng Rd 1999 Zhangjiang Hi-Tech Park Pudong New District; CN Taizhou, Zhejiang 317024 Xunqiao, Linhai
- 代理机构： Altmann Stößel Dick Patentanwälte PartG mbB
- 优先权： CN201910687575 20190729
- 国际公布： WO2020192650 20201001
- 主分类号： C07D213/64
- IPC分类号： C07D213/64 ; C07D401/14 ; C07D401/12 ; C07D405/12 ; A61K31/4412 ; A61K31/4433 ; A61K31/444 ; A61P35/00 ; A61P35/02
摘要：
The present invention relates to a preparation method for an amide compound and an application thereof in the field of medicine. Specifically, provided by the present invention is an amide small molecule compound which is an inhibitor of Zeste gene enhancer homolog 2 (EZH2) and which may be used to prevent and /or treat EZH2-mediated related diseases, comprising tumors, myeloproliferative diseases or autoimmune diseases.
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