- 专利标题: COMPLEX FOR INTRACELLULAR DELIVERY OF MOLECULES
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申请号: EP20837897.6申请日: 2020-07-10
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公开(公告)号: EP4006057A1公开(公告)日: 2022-06-01
- 发明人: GE, Shengxiang , YU, Siyuan , YANG, Han , PAN, Haifeng , REN, Shuling , LI, Tingdong , GUO, Qingshun , XIONG, Junhui , ZHANG, Jun , XIA, Ningshao
- 申请人: Xiamen University , Xiamen Innovax Biotech Co., Ltd.
- 申请人地址: CN Xiamen, Fujian 361005 No. 422, Si Ming Nan Road Siming District; CN Xiamen, Fujian 361022 1st Floor 50 Shan Bian Hong East Road Haicang District
- 代理机构: J A Kemp LLP
- 优先权: CN201910624609 20190711
- 国际公布: WO2021004539 20210114
- 主分类号: C07K19/00
- IPC分类号: C07K19/00 ; A61K47/50 ; A61K38/00 ; C12N15/11 ; C12N15/63
摘要:
A fusion protein and a complex containing same, capable of being used for the intracellular delivery of cargo molecules. The fusion protein and complex can implement the efficient release of cargo molecules from endocytic vesicles, thereby significantly improving the cytoplasmic delivery efficiency of the cargo molecules. One cargo molecules can be obtained in cytoplasms, they can exert any function related thereto. The fusion protein and complex provide effective means for affecting biological mechanisms and pathways of cells, and can be used in various fields such as research, treatment, and diagnosis.
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