- 专利标题： ANTIBODIES DIRECTED AGAINST LYMPHOCYTE ACTIVATION GENE 3 (LAG-3)
-
申请号： EP21198994.2申请日： 2016-02-03
-
公开(公告)号： EP4011914A1公开(公告)日： 2022-06-15
- 发明人: JUN, Helen Toni , KEHRY, Marilyn , BOWERS, Peter , KING, David J.
- 申请人： AnaptysBio, Inc.
- 申请人地址： US San Diego, CA 92121 10770 Wateridge Circle, Suite 210
- 代理机构： Bhogal, Jasber Kaur
- 优先权： US201562111486 P 20150203
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; A61K39/395 ; A61K45/06 ; A61P31/00 ; A61P35/00 ; A61K39/00
摘要：
The invention relates to an isolated immunoglobulin heavy chain polypeptide and an isolated immunoglobulin light chain polypeptide that bind to a protein encoded by the Lymphocyte Activation Gene-3 (LAG-3). The invention provides a LAG-3-binding agent that comprises the aforementioned immunoglobulin heavy chain polypeptide and immunoglobulin light chain polypeptide. The invention also provides related vectors, compositions, and methods of using the LAG-3-binding agent to treat a disorder or disease that is responsive to LAG-3 inhibition, such as cancer or an infectious disease.
信息查询
