公开(公告)号：EP3694877A1

公开(公告)日：2020-08-19

申请号：EP18796204.8

申请日：2018-10-09

申请人： AnaptysBio, Inc.

发明人： LONDEI, Marco

IPC分类号： C07K16/24 ,  A61P17/00 ,  A61K39/00

公开(公告)号：EP3615572A1

公开(公告)日：2020-03-04

申请号：EP18726275.3

申请日：2018-04-27

申请人： Tesaro Inc. ,  AnaptysBio, Inc.

发明人： JUN, Helen, Toni ,  KEHRY, Marilyn ,  BOWERS, Peter ,  KING, David, J. ,  BOBILEV, Dmitri ,  GHOSH, Srimoyee ,  HUANG, Baochuan ,  JENKINS, David

IPC分类号： C07K16/28 ,  A61P35/00 ,  A61K39/00

公开(公告)号：EP2992017A2

公开(公告)日：2016-03-09

申请号：EP14791454.3

申请日：2014-05-02

申请人： AnaptysBio, Inc.

发明人： KING, David J. ,  KEHRY, Marilyn

IPC分类号： C07K16/28

摘要： The invention relates to an isolated immunoglobulin heavy chain polypeptide and an isolated immunoglobulin light chain polypeptide that bind to a programmed death-1 (PD-1) protein. The invention provides a PD-1-binding agent that comprises the aforementioned immunoglobulin heavy chain polypeptide and immunoglobulin light chain polypeptide. The invention also provides related vectors, compositions, and methods of using the PD-1-binding agent to treat a cancer or an infectious disease.

公开(公告)号：EP4442712A2

公开(公告)日：2024-10-09

申请号：EP24193943.8

申请日：2016-04-01

申请人： AnaptysBio, Inc.

发明人： KEHRY, Marilyn ,  KING, David J. ,  DA SILVA CORREIA, Jean

IPC分类号： C07K16/28

CPC分类号： C07K16/2803 ,  C07K16/2818 ,  A61K2039/50720130101 ,  C07K2317/56520130101 ,  C07K2317/7620130101 ,  A61P37/00 ,  A61P35/00 ,  Y02A50/30

摘要： The invention relates to an isolated immunoglobulin heavy chain polypeptide and an isolated immunoglobulin light chain polypeptide that bind to a protein encoded by the T Cell Immunoglobulin and Mucin Protein-3 (TIM-3). The invention provides a TIM-3-binding agent that comprises the aforementioned immunoglobulin heavy chain polypeptide and immunoglobulin light chain polypeptide. The invention also provides related vectors, compositions, and methods of using the TIM-3-binding agent to treat a disorder or disease that is responsive to TIM-3 inhibition, such as cancer, an infectious disease, or an autoimmune disease.

公开(公告)号：EP4337257A1

公开(公告)日：2024-03-20

申请号：EP22732712.9

申请日：2022-05-12

申请人： AnaptysBio, Inc.

发明人： PRASEUTH, Alex ,  ZEN, Kevin ,  ALTOBELL III, Laurence ,  MARINO, Margaret H.

IPC分类号： A61K47/02 ,  A61K47/18 ,  A61K47/26 ,  A61K39/395 ,  A61P3/00 ,  A61P11/00 ,  A61P29/00 ,  A61P35/00 ,  A61P37/00

公开(公告)号：EP2992017B1

公开(公告)日：2020-11-18

申请号：EP14791454.3

申请日：2014-05-02

申请人： AnaptysBio, Inc.

发明人： KING, David J. ,  KEHRY, Marilyn

IPC分类号： C07K16/28 ,  A61P35/00

公开(公告)号：EP2601217A4

公开(公告)日：2014-03-05

申请号：EP11815158

申请日：2011-08-02

申请人： ANAPTYSBIO INC

发明人： HORLICK ROBERT ,  KING DAVID ,  BOWERS PETER ,  DALTON JENNIFER ,  WU BETTY ,  ROBERTS TRACI ,  ZHANG XUE ,  ALTOBELL III LAURENCE

IPC分类号： C07K16/00 ,  A61K39/395 ,  C12N5/16 ,  C12N15/00 ,  C12P21/06

CPC分类号： C07K16/244 ,  A61K2039/505 ,  C07K2317/21 ,  C07K2317/76 ,  C07K2317/92

公开(公告)号：EP2601217A2

公开(公告)日：2013-06-12

申请号：EP11815158.8

申请日：2011-08-02

申请人： AnaptysBio, Inc.

发明人： HORLICK, Robert ,  KING, David ,  BOWERS, Peter ,  DALTON, Jennifer ,  WU, Betty ,  ROBERTS, Traci ,  ZHANG, Xue ,  ALTOBELL III, Laurence

IPC分类号： C07K16/00 ,  A61K39/395 ,  C12N15/00 ,  C12N5/16 ,  C12P21/06

CPC分类号： C07K16/244 ,  A61K2039/505 ,  C07K2317/21 ,  C07K2317/76 ,  C07K2317/92

摘要： The disclosure relates to an isolated IL-17-binding agent which comprises an immunoglobulin heavy chain polypeptide comprising SEQ ID NO: 1 and optionally an immunoglobulin light chain polypeptide comprising SEQ ID NO: 23, except that one or more specific of residues of SEQ ID NO: 1 and SEQ ID NO: 23 are replaced with a different residue. The disclosure also provides vectors, compositions, and methods of using the IL-17-binding agent to treat an IL-17-mediated disease.

公开(公告)号：EP4176900A1

公开(公告)日：2023-05-10

申请号：EP22162381.2

申请日：2016-04-15

申请人： AnaptysBio, Inc.

发明人： Bowers, Peter ,  McKnight, Andrew John ,  King, David J. ,  Londei, Marco

IPC分类号： A61K39/395 ,  A61P9/10 ,  A61P29/00 ,  A61P37/06

摘要： The invention relates to an isolated immunoglobulin heavy chain polypeptide and an isolated immunoglobulin light chain polypeptide that bind to a protein encoded by the interleukin 36 receptor (IL-36R). The invention provides an IL-36R-binding agent that comprises the aforementioned immunoglobulin heavy chain polypeptide and immunoglobulin light chain polypeptide. The invention also provides related vectors, compositions, and methods of using the IL-36R-binding agent to treat a disorder or disease that is responsive to IL-36R inhibition, such as cancer, an infectious disease, or an autoimmune disease.

公开(公告)号：EP3770176A1

公开(公告)日：2021-01-27

申请号：EP20191195.5

申请日：2014-05-02

申请人： AnaptysBio, Inc.

发明人： KING, David J. ,  KEHRY, Marilyn

IPC分类号： C07K16/28 ,  A61P35/00 ,  A61P31/04 ,  A61P31/12

摘要： The invention relates to an isolated immunoglobulin heavy chain polypeptide and an isolated immunoglobulin light chain polypeptide that bind to a programmed death-1 (PD-1) protein. The invention provides a PD-1-binding agent that comprises the aforementioned immunoglobulin heavy chain polypeptide and immunoglobulin light chain polypeptide. The invention also provides related vectors, compositions, and methods of using the PD-1-binding agent to treat a cancer or an infectious disease.