Provided are a display substrate (20) and a display apparatus (40). The display substrate (20) comprises a first display area (21) and a second display area (22), the pixel density of the first display area (21) being greater than that of the second display area (22). A first pixel circuit (110) of a first sub-pixel of the first display area (21) comprises a pixel circuit unit (100), and a second pixel circuit (120) of a second sub-pixel of the second display area (22) comprises two pixel circuit units (100); and the first pixel circuit (110) is configured to be connected to a first power supply voltage end (103) so as to receive a first power supply voltage (VDD1) as a pixel power supply voltage, and the second pixel circuit (120) is configured to be connected to a second power supply voltage end (104) so as to receive a second power supply voltage (VDD2) as a pixel power supply voltage, the first power supply voltage (VDD1) being different from the second power supply voltage (VDD2).