发明公开
- 专利标题： FRAGMENTATION OF DNA
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申请号： EP22167477.3申请日： 2022-04-08
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公开(公告)号： EP4095254A2公开(公告)日： 2022-11-30
- 发明人: APONE, Lynne , SEXTON, Brittany S. , HEIDER, Margaret , WILLIAMS, Louise JS , DIMALANTA, Eileen T.
- 申请人： NEW ENGLAND BIOLABS, INC.
- 申请人地址： US Ipswich, MA 01938-2723 240 County Road
- 代理机构： Griffin, Philippa Jane
- 优先权： US202163193667 P 20210527
- 主分类号： C12P19/34
- IPC分类号： C12P19/34 ; C12N9/16
摘要：
Provided herein is a polymerase-free enzyme mix (FRAG) for fragmenting double-stranded DNA. In some embodiments the enzyme mix may comprise a double-stranded DNA nickase and at least one of a DNA ligase capable of sealing a nick within a DNA, and a single-strand specific DNA nuclease. Methods for fragmenting double-stranded DNA are also provided.
公开/授权文献
- EP4095254A3 FRAGMENTATION OF DNA 公开/授权日：2022-12-14
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