- 专利标题: METHOD FOR PRODUCING AZOLE DERIVATIVE, BROMOHYDRIN DERIVATIVE AND METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING 1-CHLORO-3-(4-CHLOROPHENOXY)BENZENE
-
申请号: EP21767805.1申请日: 2021-03-10
-
公开(公告)号: EP4119534A1公开(公告)日: 2023-01-18
- 发明人: MUKADE, Tsutomu , HOSHINO, Hiroshi , KOBAYASHI, Hisataka , SANO, Rumi , NEMOTO, Natsuki
- 申请人: Kureha Corporation
- 申请人地址: JP Chuo-ku Tokyo 103-8552 3-3-2, Nihonbashi-Hamacho
- 代理机构: Zimmermann & Partner Patentanwälte mbB
- 优先权: JP2020041195 20200310
- 国际公布: WO2021182530 20210916
- 主分类号: C07C41/22
- IPC分类号: C07C41/22 ; C07D249/08 ; C07C67/30 ; C07C69/734
摘要:
A novel method of producing an azole derivative represented by General Formula (I) includes: reacting an organometallic reagent formed from 1-bromo-2-chloro-4-(4-chlorophenoxy)benzene by transmetalation reaction with a bromopyruvic acid derivative to obtain a bromohydrin derivative; and reacting the bromohydrin derivative with imidazole, 1,2,4-triazole, or an alkali metal salt thereof to obtain the azole derivative.
信息查询