A microscope (1) for imaging one or more samples (70) is disclosed. The microscope (1) comprises a sample holder (30) comprising a receptacle (40) for holding the one or more samples (70), at least one illumination objective lens (10) for illuminating the one or more samples (70) with an illumination beam in an illumination light path from underneath the sample holder (30) and at least two detection objective lenses (20) arranged at the side of the sample holder (30) and for collecting light emitted from the one or more samples to image the one or more samples (70) with one or more detectors (25).