It is provided a urinalysis device (1) capable of analysing a urine sample to determine the value of physico-chemical characteristics of the urine sample and comprising a first sampler module (2) configured to be placed in fluid passage connection with a user and comprising a first drain drainage duct (20) comprising a containment part (20a) defining a predetermined volume and configured to hold a first portion of urine, and a release part (20b) configured to convey a second portion of urine out of the first sampler module (2); a diuresis bag (3) in fluid passage connection with at least the release part (20b) and configured to collect the second portion of urine; an analysis apparatus (4) placed in fluid passage connection with the containment part (20a) and configured to analyse at least part of the first urine portion; control means (5) operatively connected to the analysis apparatus (4) and configured at least to process data collected by the analysis apparatus (4); and a second sampler module (7) operatively connected to the analysis apparatus (4) and including an shut-off valve (70) in fluid passage connection with the analysis apparatus (4) and configured to accommodate a syringe engagement including sampled urine so that the analysis apparatus (4) can analyse the sampled urine.