- 专利标题： HIGHLY PARALLEL ASSAYS FOR SIMULTANEOUS IDENTIFICATION OF ANTIBODY SEQUENCES AND BINDING PARTNERS
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申请号： EP22194954.8申请日： 2016-12-21
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公开(公告)号： EP4190951A1公开(公告)日： 2023-06-07
- 发明人: FALCONER, Ester , HANSEN, Carl Lars Genghis , LECAULT, Veronique , LISAINGO, Kathleen , HEYRIES, Kevin Albert
- 申请人： The University of British Columbia
- 申请人地址： CA Vancouver BC V6T 1Z4C 103- 6109 Agronomy Road
- 代理机构： Novitas Patent AB
- 优先权： US201562270094 P 20151221
- 主分类号： C40B30/04
- IPC分类号： C40B30/04 ; C12N5/078 ; C12Q1/02 ; C12Q1/68 ; C40B20/00 ; C40B40/02 ; C40B50/06 ; G01N33/543 ; G01N33/566 ; G01N33/574 ; G01N33/68
摘要：
The present invention relates to methods for isolating the sequences of an antibody that reacts with a disease related antigen, e.g., an autoantigen, without knowing the identity of the antigen (sequence or structural epitope) a priori. The methods can also be used to identify an antigen that mediates a disease state, e.g., an autoantigen implicated in an autoimmune disorder or a tumor response.
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