Described herein are computerized methods and systems for authentication of a physical document. An image capture device coupled to a mobile device captures images of a physical document, during which the mobile device adjusts operational parameters of the image capture device, resulting in a sequence of images captured using different capture settings. The mobile device partitions the sequence of images into subsets of images, wherein each subset comprises images with a similar alignment of the physical document and captured using the same capture settings. The mobile device processes the subsets of images to identify a region of interest in each image. The mobile device generates a representation of the identified region of interest using the processed images, generates an authentication score for the document using the representation of the identified region of interest, and determines whether the physical document is authentic based upon the authentication score.