- 专利标题： PRIMARY GASTROINTESTINAL STROMAL TUMOR CELL CULTURE MEDIUM, CULTURE METHOD, AND APPLICATION THEREOF
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申请号： EP21918128.6申请日： 2021-01-22
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公开(公告)号： EP4279578A1公开(公告)日： 2023-11-22
- 发明人: LIU, Qingsong , LIU, Feiyang , LI, Xiaoyu , MEI, Husheng , WANG, Wenchao , REN, Tao , WANG, Li
- 申请人： Precedo Pharmaceuticals Co., Ltd.
- 申请人地址： CN Hefei, Anhui 230094 Room 801-816, R&D Main Building, Hefei Institute Of Technology Innovation Engineering Chinese Academy of Sciences, Xi You Road, No. 2666 Hi-Tech Industry Development Zone (HTZ)
- 代理机构： Abel & Imray LLP
- 优先权： CN202110041939 20210113
- 国际公布： WO2022151520 20220721
- 主分类号： C12N5/00
- IPC分类号： C12N5/00 ; C12N5/09
摘要：
The present invention provides a cell culture medium for culturing primary gastrointestinal stromal tumor cells, comprising gastrin, N2, insulin, a receptor tyrosine kinase ligand, and a Rock kinase inhibitor. The present invention further provides a method for culturing gastrointestinal stromal tumor cells by using the cell culture medium, and an application and a method of an expanded cell population, which is obtained by using the method, in efficacy evaluation or screening.
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