- 专利标题: COMPOUNDS AND COMPOSITIONS FOR INDUCING CHONDROGENESIS
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申请号: EP23203447.0申请日: 2018-06-07
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公开(公告)号: EP4299123A3公开(公告)日: 2024-04-03
- 发明人: CHOI, Ha-Soon , JIANG, Jiqing , LAJINESS, James Paul , NGUYEN, Bao , PETRASSI, Hank Michael James , WANG, Zhicheng
- 申请人: Novartis AG
- 申请人地址: CH 4056 Basel Lichtstrasse 35
- 代理机构: Mueller, Philippe
- 优先权: US201762517394 P 20170609
- 主分类号: C07D493/08
- IPC分类号: C07D493/08 ; A61K45/06 ; A61P19/02
摘要:
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof;
or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds; and methods of using such compounds for treating joint damage or injury in a mammal, for inducing hyaline cartilage production or for inducing differentiation of chondrogenic progenitor cells into mature chondrocytes.
or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds; and methods of using such compounds for treating joint damage or injury in a mammal, for inducing hyaline cartilage production or for inducing differentiation of chondrogenic progenitor cells into mature chondrocytes.
公开/授权文献
- EP4299123A2 COMPOUNDS AND COMPOSITIONS FOR INDUCING CHONDROGENESIS 公开/授权日:2024-01-03
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