- 专利标题： METHODS AND COMPOSITIONS FOR EFFICIENT DELIVERY OF NUCLEIC ACIDS AND RNA-BASED ANTIMICROBIALS
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申请号： EP23192508.2申请日： 2016-06-15
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公开(公告)号： EP4299754A3公开(公告)日： 2024-03-20
- 发明人: BEISEL, Chase Lawrence , GOMAA, Ahmed Abdelshafy Mahmoud , LUO, Michelle
- 申请人： North Carolina State University
- 申请人地址： US Raleigh, NC 27606 1021 Main Campus Drive 2nd Floor
- 代理机构： HGF
- 优先权： US201562175749 P 20150615
- 主分类号： C12N1/21
- IPC分类号： C12N1/21 ; C12N7/01 ; C12N15/63 ; C12P19/34
摘要：
The invention relates to the methods for modifying the methylation pattern of bacteriophage DNA and phagemid DNA and to methods for selective killing of bacteria using lysogenic bacteriophages comprising bacteriophage DNA or phagemid DNA comprising components of an engineered CRISPR-Cas system.
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