- 专利标题: SOLID FORMS OF AN FGFR INHIBITOR AND PROCESSES FOR PREPARING THE SAME
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申请号: EP23197192.0申请日: 2019-05-03
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公开(公告)号: EP4309737A3公开(公告)日: 2024-03-27
- 发明人: BURN, Timothy C. , LIU, Phillip C. , FRIETZE, William , JIA, Zhongjiang , TAO, Ming , WANG, Dengjin , ZHOU, Jiacheng , LI, Qun
- 申请人: Incyte Corporation
- 申请人地址: US Wilmington, DE 19803 1801 Augustine Cut-Off
- 代理机构: Carpmaels & Ransford LLP
- 优先权: US201962815539 P 20190308
- 主分类号: C07D471/14
- IPC分类号: C07D471/14 ; A61K31/519 ; A61P35/00
摘要:
The present disclosure relates to 3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-ethyl-8-(morpholin-4-ylmethyl)-1,3,4,7-tetrahydro-2H-pyrrolo[3',2':5,6]pyrido[4,3-d]pyrimidin-2-one, solid forms and polymorphs thereof, methods of preparation thereof, and intermediates in the preparation thereof, which are useful in the treatment of the FGFR-associated or mediated diseases such as cancer.
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