- 专利标题: SYNTHESIS, PHARMACOLOGY AND USE OF NEW WATER-SOLUBLE AND SELECTIVE FMS-LIKE TYROSINE KINASE 3 (FLT3) INHIBITORS
-
申请号: EP22215045.0申请日: 2022-12-20
-
公开(公告)号: EP4389223A1公开(公告)日: 2024-06-26
- 发明人: The designation of the inventor has not yet been filed
- 申请人: Universität Regensburg
- 申请人地址: DE 93053 Regensburg Universitätsstrasse 31
- 专利权人: Universität Regensburg
- 当前专利权人: Universität Regensburg
- 当前专利权人地址: DE 93053 Regensburg Universitätsstrasse 31
- 代理机构: Engelhard, Markus
- 主分类号: A61P35/00
- IPC分类号: A61P35/00 ; C07D413/14 ; A61K31/422 ; A61K31/496 ; A61K31/506 ; A61K31/454 ; A61K31/5377 ; A61K31/5513
摘要:
The present application relates to compounds of formula (I), which inhibit FLT3. The present application further relates to a composition, preferably pharmaceutical composition, comprising a compound of formula (I) or a pharmaceutically acceptable salt thereof and comprising a pharmaceutically acceptable excipient and/or carrier. The present application also relates to a compound of formula (I) or composition thereof for use in medicine. The present application also relates to a compound of formula (I) or composition thereof for use in a method of preventing or treating cancer, preferably blood cancer, more preferably leukemia, even more preferably acute myeloid leukemia (AML). Furthermore, the present application relates to a method of preparing a compound of formula (I).
信息查询
IPC分类:
A | 人类生活必需 |
A61 | 医学或兽医学;卫生学 |
A61P | 化合物或药物制剂的特定治疗活性 |
A61P35/00 | 抗肿瘤药 |