An assembly and method for delivery of an analyte sensor including a reusable applicator configured to insert at least a portion of an analyte sensor under a skin surface and in contact with a bodily fluid, the reusable applicator comprising: a housing; an actuator configured to move in a distal direction relative to the housing; a sharp carrier releasably coupled with a sharp module; a reusable applicator base releasably engaged with a disposable sensor carrier, the disposable sensor carrier configured to releasably retain a sensor control device; and the sensor control device comprising the analyte sensor. The sensor control device is configured to advance in the distal direction from a first position within the reusable applicator to a second position adjacent to the skin surface after application of a first force on the actuator, and the reusable applicator is configured to eject the disposable sensor carrier and the sharp module therefrom in response to application of a second force on the actuator.