- 专利标题: COMPOSITIONS AND METHODS FOR ENHANCING PRODUCTION, GROWTH, SPREAD, OR ONCOLYTIC AND IMMUNOTHERAPEUTIC EFFICACY OF INTERFERON-SENSITIVE VIRUSES
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申请号: EP24188307.3申请日: 2018-11-23
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公开(公告)号: EP4431598A2公开(公告)日: 2024-09-18
- 发明人: DIALLO, Jean-Simon , SELMAN, Mohammed , ARULANANDAM, Rozanne , FORBES, Nicole Elise , KRISHNA, Ramya
- 申请人: Ottawa Hospital Research Institute
- 申请人地址: CA Ottawa, Ontario K1H 8L6 501 Smyth Road
- 专利权人: Ottawa Hospital Research Institute
- 当前专利权人: Ottawa Hospital Research Institute
- 当前专利权人地址: CA Ottawa, Ontario K1H 8L6 501 Smyth Road
- 代理机构: Kransell & Wennborg KB
- 优先权: US 1762590456P 2017.11.24
- 分案原申请号: 18880792.9 2018.11.23
- 主分类号: C12N7/00
- IPC分类号: C12N7/00
摘要:
Provided herein are fumaric and maleic acid-containing compounds, compositions comprising the same and methods for using such compounds to enhance production, growth, spread or titer of interferon-sensitive viruses in cells, particularly cancer and tumor cells. Also provided are methods of treating tumors or cancers in a subject by administering the compounds and compositions.
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