- 专利标题： NOVEL LACTOBACILLUS PLANTARUM STRAIN AND USE THEREOF
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申请号： EP22895764.3申请日： 2022-05-20
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公开(公告)号： EP4435090A1公开(公告)日： 2024-09-25
- 发明人: KIM, Hyerim , LEE, Suro , YEON, Jaesung , KIM, Hyeyoung , LEE, Donghun
- 申请人： Genome and Company
- 申请人地址： KR Seongnam-si, Gyeonggi-do 13486 B-8F, 35, Pangyo-ro 255beon-gil, Bundang-gu
- 专利权人： Genome and Company
- 当前专利权人： Genome and Company
- 当前专利权人地址： KR Seongnam-si, Gyeonggi-do 13486 B-8F, 35, Pangyo-ro 255beon-gil, Bundang-gu
- 代理机构： Rückerl, Florian
- 优先权： KR 210160740 2021.11.19
- 国际申请： KR2022007256 2022.05.20
- 国际公布： WO2023090552 2023.05.25
- 主分类号： C12N1/20
- IPC分类号： C12N1/20 ; A61K35/742 ; A61P15/08 ; A23L33/135 ; C12R1/25
摘要：
The present invention relates to a novel Lactobacillus plantarum strain. In addition, the present invention relates to a composition for preventing, improving, or treating infertility or subfertility comprising the Lactobacillus plantarum strain.
The Lactobacillus plantarum strain of the present invention reduces the expression of specific genes in cells constituting the placenta to help implantation of the embryo, increases the number of immune cells in the uterus, and enhances the implantation rate of embryos reduced by immune imbalance. Accordingly, it can be effectively utilized as a composition for the prevention, improvement, or treatment of infertility or subfertility.
The Lactobacillus plantarum strain of the present invention reduces the expression of specific genes in cells constituting the placenta to help implantation of the embryo, increases the number of immune cells in the uterus, and enhances the implantation rate of embryos reduced by immune imbalance. Accordingly, it can be effectively utilized as a composition for the prevention, improvement, or treatment of infertility or subfertility.
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