公开(公告)号：EP4435090A1

公开(公告)日：2024-09-25

申请号：EP22895764.3

申请日：2022-05-20

申请人： Genome and Company

发明人： KIM, Hyerim ,  LEE, Suro ,  YEON, Jaesung ,  KIM, Hyeyoung ,  LEE, Donghun

IPC分类号： C12N1/20 ,  A61K35/742 ,  A61P15/08 ,  A23L33/135 ,  C12R1/25

CPC分类号： A61P15/08 ,  C12N1/20 ,  C12R2001/02520210501 ,  A61K35/742 ,  A23L33/135

摘要： The present invention relates to a novel Lactobacillus plantarum strain. In addition, the present invention relates to a composition for preventing, improving, or treating infertility or subfertility comprising the Lactobacillus plantarum strain.
The Lactobacillus plantarum strain of the present invention reduces the expression of specific genes in cells constituting the placenta to help implantation of the embryo, increases the number of immune cells in the uterus, and enhances the implantation rate of embryos reduced by immune imbalance. Accordingly, it can be effectively utilized as a composition for the prevention, improvement, or treatment of infertility or subfertility.