发明专利
JP2005040134A 3-phosphoglycerate dehydrogenase variant whose inhibition by l-serine is reduced, and gene encoding them and use of the same 有权
由L-丝氨酸抑制的3-磷酸脱氢酶脱氢酶的变异及其编码及其使用的基因

3-phosphoglycerate dehydrogenase variant whose inhibition by l-serine is reduced, and gene encoding them and use of the same
摘要:
PROBLEM TO BE SOLVED: To provide an Escherichia coli PGD variant having a reduced susceptibility to inhibition by serine compared with Escherichia coli wild-type. SOLUTION: This object is achieved by means of a PGD which has an amino acid sequence which differs from the amino acid sequence of the Escherichia coli wild-type PGD (comprising a specific sequence) having a methionine as position 1, in that an amino acid apart from glycine is present at position 349 or an amino acid apart from threonine is present at position 372. COPYRIGHT: (C)2005,JPO&NCIPI
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