式（I）的：的化合物或其药学上可接受的盐在本文中描述。 ,, N，R 1中，R 4a，R4B，R5，R7和R8与式（I）如本文所定义。 本公开的化合物具有活性SHIP1调节剂，因此可用于治疗任何的各种各样的，将来自调节SHIP1受益的疾病，障碍或病症。 式（I）的化合物，含有与药学上可接受的载体或稀释剂组合的组合物还通过在需要这样的化合物给予动物体，SHIP调节的1种方法中公开 它也被公开。

Of formula (I):

The compound or a pharmaceutically acceptable salt of are described herein. In the formula (I),

^{, N, R 1, R 4a} , R 4b, R 5, R 7 and ^{R 8} are as defined herein. The compounds of the present disclosure may possess activity as SHIP1 modulators, thus, it may be used to treat any of a variety of diseases, disorders or conditions that would benefit from SHIP1 regulation. The compounds of formula (I), compositions containing, in combination with a pharmaceutically acceptable carrier or diluent are also disclosed, by administering such compounds to an animal in need thereof, SHIP 1 method of modulating It is also disclosed.