Invention Grant
- Patent Title: Methods of using microneedle vaccine formulations to elicit in animals protective immunity against rabies virus
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Application No.: US14930831Application Date: 2015-11-03
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Publication No.: US10010499B2Publication Date: 2018-07-03
- Inventor: Yu-Wei Chiang , Mark R. Prausnitz , Kristopher Daniel DeWitt , Jaya Arya
- Applicant: MERIAL, INC. , Georgia Tech Research Corporation
- Applicant Address: US GA Duluth US GA Atlanta
- Assignee: MERIAL INC.,Georgia Tech Research Corporation
- Current Assignee: MERIAL INC.,Georgia Tech Research Corporation
- Current Assignee Address: US GA Duluth US GA Atlanta
- Agency: Merial Inc.
- Agent Judy Jarecki-Black; Ruoying Chen
- Main IPC: C12N7/00
- IPC: C12N7/00 ; A61K9/00 ; A61K39/205 ; A61K39/12 ; A61M37/00 ; A61K39/00 ; A61B5/15 ; A61B17/20

Abstract:
The present invention relates to microneedle vaccine formulations, as well as methods of use thereof to provide animals, including canines, protective immunity against infection and disease caused by rabies viruses. Once placed onto the skin of the animals, the microneedle formulations dissolve quickly into the surrounding skin, where the antigens then elicit in the animals high and protective levels of rabies virus neutralizing antibodies.
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