- 专利标题： Factor VIII chimeric and hybrid polypeptides, and methods of use thereof
-
申请号： US14131600申请日： 2012-07-06
-
公开(公告)号： US10010622B2公开(公告)日： 2018-07-03
- 发明人: Jennifer A. Dumont , Susan Low , Alan J. Bitoni , Glenn Pierce , Alvin Luk , Haiyan Jiang , Byron McKinney , Matt Ottmer , Jurg Sommer , Karen Nugent , Lian Li , Robert Peters
- 申请人： Jennifer A. Dumont , Susan Low , Alan J. Bitoni , Glenn Pierce , Alvin Luk , Haiyan Jiang , Byron McKinney , Matt Ottmer , Jurg Sommer , Karen Nugent , Lian Li , Robert Peters
- 申请人地址： US MA Waltham
- 专利权人： Bioverativ Therapeutics Inc.
- 当前专利权人： Bioverativ Therapeutics Inc.
- 当前专利权人地址： US MA Waltham
- 代理机构： Sterne, Kessler, Goldstein & Fox P.L.L.C.
- 国际申请： PCT/US2012/045784 WO 20120706
- 国际公布： WO2013/009627 WO 20130117
- 主分类号： C07K14/755
- IPC分类号： C07K14/755 ; A61K47/48 ; A61K38/37 ; G01N33/86 ; A61K47/60 ; A61K47/68
摘要：
The present invention provides methods of administering Factor VIII (processed FVIII, single chain FVIII, or a combination thereof); methods of administering chimeric and hybrid polypeptides comprising Factor VIII; chimeric and hybrid polypeptides comprising Factor VIII; polynucleotides encoding such chimeric and hybrid polypeptides; cells comprising such polynucleotides; and methods of producing such chimeric and hybrid polypeptides using such cells.
公开/授权文献
信息查询
