Invention Grant
- Patent Title: Compounds and compositions as inhibitors of MEK
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Application No.: US15460633Application Date: 2017-03-16
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Publication No.: US10011599B2Publication Date: 2018-07-03
- Inventor: Mark Gary Bock , Henrik Moebitz , Sunil Kumar Panigrahi , Ramulu Poddutoori , Susanta Samajdar
- Applicant: NOVARTIS AG
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Scott W. Reid
- Priority: IN2418/DEL/13 20130814; IN1686/DEL/14 20140624
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61K31/4745 ; A61K31/506 ; A61K31/513 ; A61K31/497 ; A61K31/53
Abstract:
The present invention relates to compounds of formula I: in which n, R1, R2, R3a, R4 and R5 are defined in the Summary of the Invention; capable of inhibiting the activity of MEK. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of hyperproliferative diseases like cancer.
Public/Granted literature
- US20170183348A1 COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF MEK Public/Granted day:2017-06-29
Information query
