Provided are a method and device for processing pre-handover, User Equipment (UE) and a cell. The method includes that: UE receives pre-handover target cell configuration information sent by a serving cell; and the UE executes pre-handover procedure according to the pre-handover target cell configuration information. By the disclosure, the problems of low handover success rate and poor handover robustness of inter-cell handover in the related art are solved, and effects of enhancing robustness of inter-cell handover, increasing a success rate of inter-cell handover and improving network performance and a user experience are further achieved.