- 专利标题： Inhibitors of ACK1/TNK2 tyrosine kinase
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申请号： US15808421申请日： 2017-11-09
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公开(公告)号： US10017478B2公开(公告)日： 2018-07-10
- 发明人: Nupam P. Mahajan , Kiran N. Mahajan , Nicholas J. Lawrence , Harshani R. Lawrence
- 申请人： H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC.
- 申请人地址： US FL Tampa
- 专利权人： H. Lee Moffitt Cancer Center and Research Institute, Inc.
- 当前专利权人： H. Lee Moffitt Cancer Center and Research Institute, Inc.
- 当前专利权人地址： US FL Tampa
- 代理机构： Meunier Carlin & Curfman LLC
- 主分类号： C07D405/12
- IPC分类号： C07D405/12 ; C07D239/49 ; C07D239/42 ; C07D405/14 ; C07C53/18 ; C07D239/48
摘要：
Described are cancer therapies and anti-cancer compounds. In particular, disclosed are inhibitors of Ack1 tyrosine kinase and their use in the treatment of cancer. Methods of screening for new Ack1 tyrosine kinase inhibitors are also disclosed. In specific example, compound having Formula I through IV are disclosed.
公开/授权文献
- US20180155297A1 INHIBITORS OF ACK1/TNK2 TYROSINE KINASE 公开/授权日：2018-06-07
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