Provided are a method and device for processing measurement configuration. The method includes: after a HO flow or a reselection flow is triggered in a source cell, UE processes a WLAN interworking mechanism measurement configuration in at least one of manners as follows: the UE continues using a current WLAN interworking mechanism measurement configuration; the UE modifies a target frequency point in the current WLAN interworking mechanism measurement configuration into the whole frequency band for measurement; the UE requests for a WLAN interworking mechanism measurement configuration corresponding to a target cell; and the UE suspends WLAN interworking mechanism measurement until the UE receives the WLAN interworking mechanism measurement configuration corresponding to the target cell.